Latest news and research on all cancers and treatments, updated several times a week
It might be hard to tell these days, but cancer immunotherapy can be disappointing, too. In a lunchtime review Monday at the American Society of ...
Despite keeping publicly mum about the specifics of its approach, cancer immunotherapy startup Potenza Therapeutics has certainly piqued the ...
Cancer immunotherapy is one such development in the field of cancer treatment. This treatment option involves manipulating the human body's ...
A single cycle of the CD19-based immunotherapy blinatumomab resulted in complete minimal residual disease (MRD) response in 78% of patients ...
A multicenter phase 1 trial of the immune checkpoint blocker ipilimumab found clinical benefit in nearly half of blood cancer patients who had relapsed ...
In the first phase of the trial, Gardner treated 13 patients with relapsed acute lymphoblastic leukemia usingcancer immunotherapy. This phase was ...
"The data from the '211 study expand the evidence of Amgen's BiTE®immunotherapy as an advance in the management of this difficult-to-treat cancer ...
The Seattle cancer immunotherapy company aims to sell shares at $15 to $18 apiece. At the high end, that would give it a market capitalization of ...
SAN DIEGO--(BUSINESS WIRE)--OncoSec Medical Inc. (OTCQB: ONCS), a company developing DNA-based intratumoral cancer immunotherapies, ...
Through the deal, Pfizer gets some early-stage drugs that target IDO1 and TDO2, cancer-expressed enzymes that break down tryptophan, which is ...
A multicenter phase 1 trial of the immune checkpoint blocker ipilimumab found clinical benefit in nearly half of blood cancer patients who had relapsed ...
The authors of a large, international study found that pioglitazone (Actos) and rosiglitazone (Avandia) did not lead to an increased risk for bladder ...
The latest stage of Dunedin cancer diagnostic company Pacific Edge's development of a ''one stop shop'' forbladder cancer detection was launched ...
Bladder cancer is the sixth most common cancer in the US, with 74,690 new cases and 15,580 deaths estimated for 2014. Urologists also treat ...
... Action Network, Association of Community Cancer Centers, Bladder CancerAdvocacy Network, Bristol-Myers Squibb, Cancer Support Community, ...
What we wanted to see is how the immune system responded to being re-challenged to the cancer cells and as you may or may not know one of the ...
A microscope image shows many of the immune system's dendritic cells that were collected from a 3D scaffold three days after in vivo injection.
Cancer Immunotherapy Market & Clinical Pipeline Insight ... involves manipulating the human body'simmune system in order to target the cancer.
It might be hard to tell these days, but cancer immunotherapy can be ... Some tumor cells produce these proteins to hide from the immune system and ...
Hodgkin Lymphoma is a lymphatic cancer or in other words a cancer of lymphocytes (aka White Blood Cells), mostly found in the young adults and ...
In layman's terms, nivomulab helps to aid a patient's own immune system better attack the cancer inside them. In the meantime, as any friend or family ...
Yet lung cancer lags behind other forms of cancer in research and ... is a separate class of drugs that stimulate the immune system to fight the cancer.
Driving CARs to ALL Remission
Gene engineering technology yields positive results in pediatric patients.
Gene engineering technology yields positive results in pediatric patients.
Drug, first in a new class of bi-specific medications, proves active in acute lymphocytic leukemia. Full story
Wearing a 'cold cap' may reduce side-effects of chemo drugs
Chelsea Martin, 30, from London was persuaded to try 'scalp cooling'
Lightweight silicone cap can be filled with a liquid cooling gel
Helps reduce the amount of chemotherapy drugs reaching the follicles
“a new test offers another way of predicting how aggressive a cancer is - and how urgent it is for men to go through potentially damaging surgery. Called Prolaris, the test is used with existing results from PSA tests, the Gleason score and the biopsy to give a clearer likely prognosis. It uses tissue already taken in a biopsy. But rather than looking at the structure of the cells, it examines the cancer in greater detail, adding chemicals to break open the cells and extract the DNA. Scientists then examine 31 genes and the proteins they produce, which are thought to trigger the abnormal cells to divide and grow quickly
“A multitasking plasma membrane protein coordinates cell division and energy metabolism in healthy—and perhaps also cancerous—Drosophila cells
Prostate Cancer Screening - What Does the Evidence Tell Us?
In May 2012, the United States Preventive Services Task Force (USPSTF) released a recommendation against prostate-specific antigen (PSA) screening for men. This article reviews the evidence and also evaluates new data that has become available since the USPSTF recommendation was released.
In May 2012, the United States Preventive Services Task Force (USPSTF) released a recommendation against prostate-specific antigen (PSA) screening for men. This article reviews the evidence and also evaluates new data that has become available since the USPSTF recommendation was released.
CDK 4/6 Inhibitors for Breast Cancer
This can't miss podcast discusses the impact that CDK 4/6 inhibitors are having on specific types of breast cancer with Dr. Richard Finn, an associate professor of medicine at the Geffen School of Medicine and a medical oncologist at the University of California Los Angeles Jonsson Comprehensive Cancer Center.
This can't miss podcast discusses the impact that CDK 4/6 inhibitors are having on specific types of breast cancer with Dr. Richard Finn, an associate professor of medicine at the Geffen School of Medicine and a medical oncologist at the University of California Los Angeles Jonsson Comprehensive Cancer Center.
A campaign urging people with a persistent cough to visit a doctor has seen a surge of early stage lung cancer diagnoses.
Cancer News in Science Daily
“Using a gene-editing system originally developed to delete specific genes, researchers have now shown that they can reliably turn on any gene of their choosing in living cells. The findings are expected to help researchers refine and further engineer the tool to accelerate genomic research and bring the technology closer to use in the treatment of human genetic disease.
“A new combination of cancer drugs delayed disease progression for patients with hormone-receptor-positive metastatic breast cancer, according to a multi-center phase II trial. The drug combination doubled the number of patients whose cancer had not progressed after one year from 14% to 28%, according to the study.
“Evidence suggesting that the male hormone testosterone may actually be a contributing factor in the formation of colon cancer tumors has been discovered. "Previously, scientists believed that female hormones may have lent some sort of protection against tumor susceptibility," the lead researcher said. "However, by showing that removing testosterone from rats leads to a drastic decrease in colon cancer susceptibility, it appears that male hormones may actually contribute to colon tumor growth rather than female hormones being protective."
“A marker of immune function that predicts for better outcomes in patients treated with chemotherapy for triple negative breast cancer is also linked to improved prognosis in patients treated with chemotherapy for HER2-positive breast cancer.
“Triple negative breast cancer cells process tryptophan to promote survival while traveling through the body in order to seed new tumor sites, researchers say. “I’m not saying that people with metastatic breast cancer shouldn’t eat turkey during the holidays, but triple-negative breast cancer appears to have found a way to process tryptophan more quickly, equipping cancer cells to survive while in circulation, which allows them to metastasize,” says the first author of a new paper.
“Researchers have developed a method for spying on the activity of every gene within a cell at once. The breakthrough allows them to determine the order in which the three layers of cells in animal embryos evolved. Other applications include cancer research.
“A new mechanism that gives a better understanding of cancer development has been identified by scientists. The molecular mechanism ensures that when cells divide, the genomic material passes correctly to the resulting daughter cells: "The process, known as chromosome segregation, is vitally important because incorrect passage of the genomic material makes cells prone to develop into cancer cells," says one investigator. The new discovery depends on a protein called BubR1 which if mutated can cause cancer.
“Breast cancer is the most common form of cancer in women. One in nine will suffer breast cancer over their lifetime. Progress in prevention and early detection, and the use of chemotherapy after surgery (adjuvant chemotherapy), have achieved significantly increase survival in this disease in the last ten years, but much remains to be done. The identification of patients with high-risk breast cancer is key to knowing whether a patient will require only the removal of the tumor by surgery or whether if she will need additional chemotherapy to make sure the removal of breast cancer cells.
Majority of women with early-stage breast cancer in U.S. eceive unnecessarily long courses of radiation
“Two-thirds of women treated for early-stage breast cancer in the U.S. receive longer radiation therapy than necessary, according to a new study. "Hypofractionated radiation is infrequently used for women with early-stage breast cancer, even though it's high-quality, patient-centric cancer care at lower cost," said the study's lead author. "It is clinically equivalent to longer duration radiation in curing breast cancer, has similar side effects, is more convenient for patients, and allows patients to return to work or home sooner."
“In patients with metastatic triple-negative breast cancer, infusion of pembrolizumab produced durable responses in almost one out of five patients. One of the 27 patients had a complete response and four had a partial response. Seven more patients had stable disease.
Women with dense breasts will have to look beyond ultrasound for useful supplemental breast cancer screening
“Supplemental ultrasound screening for all U.S. women with dense breasts would substantially increase healthcare costs with little improvement in overall health, according to researchers. The study will help inform the national legislative discussion about potential regulations requiring health providers to tell women if their mammogram shows that they have dense breasts.
“Clinical recommendations discouraging the use of CYP2D6 gene testing to guide tamoxifen therapy in breast cancer patients are based on studies with flawed methodology and should be reconsidered, according to the results of a new study.
“In a groundbreaking new study, researchers have for the first time advanced a surgical technique performed with the help of a robot to successfully access a previously-unreachable area of the head and neck.
“The first long-term study of a pioneering endoscopic laser treatment for early vocal-cord cancer, previously shown to provide optimal voice outcomes, finds that it is as successful as traditional approaches in curing patients' tumors while avoiding the damage to vocal quality caused by radiotherapy or by conventional laser or cold-instrument surgery.
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